Archive for December, 2010

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The current business model on which biotech has relied is flawed. Due to poor rates of Areturn, investment has dried up as the model carries very high risk of failure. This was illustrated recently by a study that highlighted that of the 1,606 biotech investments realised between 1986 and 2008, 704 investments resulted in a full or partial loss, while 16 only just covered their costs.

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Posted: December 25th, 2010
at 7:57pm by Koookiecrumbles


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I think of gratefulness now as an acquired skill, like say, playing guitar. There was a time I didn't know how to do it. Then there was a time I began to learn how to do it. And now it's a simple case of the more I do it, the better I get at it, and the better I get at it, the happier I am. And the happier I am, the happier the people around me are.

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Posted: December 25th, 2010
at 2:39pm by Koookiecrumbles


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Progress in Algorithms Beats Moore's Law

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Everyone knows Moore's Law - a prediction made in 1965 by Intel co-founder Gordon Moore that theAdensity of transistors in integrated circuits would continue to double every 1 to 2 years.A(…) AEven more remarkable - and even less widely understood - is that in many areas, performance gains dueAto improvements in algorithms have vastly exceeded even the dramatic performance gains due to increasedAprocessor speed.

The algorithms that we use today for speech recognition, for natural language translation, for chessAplaying, for logistics planning, have evolved remarkably in the past decade. AIt's difficult to quantify theAimprovement, though, because it is as much in the realm of quality as of execution time.

In the field of numerical algorithms, however, the improvement can be quantified. AHere is just oneAexample, provided by Professor Martin Grotschel of Konrad-Zuse-Zentrum fur Informationstechnik Berlin. AGrotschel, an expert in optimization, observes that a benchmark production planning model solvedAusing linear programming would have taken 82 years to solve in 1988, using the computers and the linearAprogramming algorithms of the day. AFifteen years later - in 2003 - this same model could be solved inAroughly 1 minute, an improvement by a factor of roughly 43 million. AOf this, a factor of roughly 1,000 wasAdue to increased processor speed, whereas a factor of roughly 43,000 was due to improvements in algorithms! AGrotschel also cites an algorithmic improvement of roughly 30,000 for mixed integer programmingAbetween 1991 and 2008.

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Posted: December 25th, 2010
at 2:36pm by Koookiecrumbles


Categories: computers,development

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The dominance of the screens is only beginning. The big question is how we'll react to their increasing numbers. I have long thought that our current addiction is connected to the novelty of this expanding technological playground. Once we get used the screens and the always-on access they provide, we'll be better equipped to compartmentalize them. We'll use screens when we need them and let them go black when we don't.

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Posted: December 25th, 2010
at 2:30pm by Koookiecrumbles


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The initial impulse to write "Understand" arose from an offhand remark made by my roommate in college; he was reading Sartre’sANausea at the time, whose protagonist finds only meaninglessness in everything he sees. But what would it be like, my roommate wondered, to find meaning and order in everything you saw? To me that suggested a kind of heightened perception, which in turn suggested superintelligence. I started thinking about the point at which quantitative improvements — better memory, faster pattern recognition — turn into a qualitative difference, a fundamentally different mode of cognition.

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Posted: December 25th, 2010
at 2:23pm by Koookiecrumbles


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Too much regulation can stifle small business.A Too little can lead to bank meltdowns.A A completely free Internet can be anti-consumer.A A tiered internet can create high barriers to entry for tech start-ups delivering content.

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Posted: December 24th, 2010
at 9:47pm by Koookiecrumbles


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Business/Life Coaches Just Want Your Money

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I’m skeptical of people who talk for a living. If you wrote a self-help book and now give lectures around the world talking about your book, chances are I want nothing to do with you unless everything you say is grounded onAhard science. If what you say cannot be proven or disproven, I’m not interested, even if all of it might be true. This includes alternative medicine advocates, nutritionists, personality coaches, most business / leadership coaches, NLP counsellors, and definitely the followers ofApseudosciences like astrology, faith / spiritual healing, dowsing, ghost hunting, homeopathy, magnet therapy, and ESP. I know many people in my personal life believe in some of the above but it doesn’t bother me. After all, I’m a fan of a time-travellingADoctor from the extraterrestrial planetGallifrey so who am I judge what someone else believes in.

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Posted: December 24th, 2010
at 4:16pm by Koookiecrumbles


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Why is it bad to go with entropy, to embrace it and let one life be driven by it ? It's pretty obvious, I think: we lose all little control we have on our lives. It's clear we cannot be in full control of external things, yet at least we can be in full control of Ahow we react to entropy.

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Posted: December 24th, 2010
at 1:55pm by Koookiecrumbles


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Write comically straightforward code, as if you just learned to program, and go out of your way avoid wearing any kind of software engineering hat-unless what you really want to be is a software engineer, and not the designer of an experience.

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Posted: December 24th, 2010
at 1:50pm by Koookiecrumbles


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