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Selection of a DNA aptamer for homocysteine using SELEX from Maureen McKeague on Vimeo.

The lab is exploring a chemical technique called SELEX-systematic evolution of ligands by exponential enrichment-which generates short segments of DNA and RNA called aptamers. These nucleic acids can be designed to stick to almost any target molecule. For McKeague’s Ph.D. research, the target molecule-played by undergraduate student and Scottish folk dancer Charlotte Bradley-is the amino acid homocysteine. High levels of this amino acid are an indicator of cardiovascular disease. McKeague’s aim is to use SELEX to create aptamers to cheaply and accurately measure homocysteine in blood samples. [SOURCE]


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Posted: December 28th, 2010
at 2:41pm by Black Ock

Categories: science,ninjas are everyehere

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